Formulating cannabinoids with lipid excipients

Cannabinoids are very susceptible to degradation in presence of oxygen, light, heat, or at low pH. And most importantly, their degradation metabolites have different effects and potencies. It is therefore critical to prevent degradation during handling and processing and to formulate with care.

CBD ad THC are very sensitive to heat, and should be incorporated at temperatures below 60°C in the formulation to prevent degradation. Furthermore, we have carried out stability studies showing that our lipid excipients provide >95% THC stability, over 3 months at room temperature, eventually admixed with a combination of antioxidants with complementary modes of action.

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