A Case Report of Cannabis Abuse: A Surprising Etiology of Elevated Troponin

Case Reports

. 2023 Jan 5;15(1):e33423.

doi: 10.7759/cureus.33423.

eCollection 2023 Jan.


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Case Reports

Nway Nway et al.




Cannabis is the most commonly used additive drug after alcohol and tobacco. There has been literature proving the relationship between cannabis use and elevated troponin from myocardial infarction, with many mechanisms explaining them. However, limited data are available on elevated troponin due to cannabis-induced high myocardial oxygen demand due to vasospasm. We present a case of a 21-year-old female presenting with chest pain after cannabis abuse. She exhibited a steep rise in troponin with a normal electrocardiogram (EKG). She refused a coronary angiogram, but a bedside echocardiogram showed no wall motion abnormality. Therefore, the dramatic rise of troponin levels with the chest pain and the resolution of the symptoms were most likely explained by demand ischemia via the mechanism of reversible vasospasm.


: acute coronary syndrome; cannabis use; cardiac troponin; high troponin; substance-abuse”.

Conflict of interest statement

The authors have declared that no competing interests exist.


Figure 1

Figure 1. Electrocardiogram (EKG) at presentation showing sinus rhythm

Figure 2

Figure 2. Graphical representation of troponin levels trend

Figure 3

Figure 3. The Computed Tomography Angiogram (CTA) scan of the chest showed no evidence of pulmonary embolism

Figure 4

Figure 4. Electrocardiogram (EKG) on Day 4 showing Normal sinus rhythm.

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